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• This will be the fifth meeting between Croatia and Wales on the international stage, with Croatia winning the last three matches following a 1-1 draw in their first match in 2002.
• Wales haven't lost four consecutive matches against a single opponent since June 2016 versus England, losing their last five against the Three Lions.
• Wales have lost three of their last four away matches in all competitions (W1), as many defeats as they'd registered in their previous 12 such matches combined (W5 D4 L3).
• Wales have lost just once in their last 13 European Championship qualifiers (W9 D3 L1), losing to Bosnia and Herzegovina in October 2015 under Chris Coleman (0-2).
• Ryan Giggs could become the first Wales manager to win his first two European Championship qualifying matches in charge since Terry Yorath in 1990.
• Wales' Gareth Bale has had a hand in 12 goals in his last 14 appearances for the national team (9 goals, 3 assists), including registering seven goal involvements in his last seven matches.
• Andrej Kramaric was directly involved in 21 league goals for Hoffenheim in 2018-19 (17 goals, 4 assists), more than any other Croatian player in Europe's big five leagues.
• Ashley Williams (85) could earn his 86th cap in this match, becoming the outright second leading appearance maker amongst outfield players for the Wales national team (men's) behind only Chris Gunter.